Journal of Pharmaceutical Microbiology be held by Imed Pub Publishing SL which is one of the leading international publishers of open access journals. We are overjoyed to promulgate that our Journal of Pharmaceutical Microbiology got outstretched for 5 volumes which is an enormous triumph on account of esteemed authors who made endowment to our journal more honored.
Pharmaceutical Microbiology is an applied branch of Microbiology. It involves the study of microorganisms associated with the manufacture of pharmaceuticals e.g. minimizing the number of microorganisms in a process environment, excluding microorganisms and microbial biproducts like exotoxin and endotoxin from water and other starting materials, and ensuring the finished pharmaceutical product is sterile. Other aspects of pharmaceutical microbiology include the research and development of anti-infective agents, the use of microorganisms to detect mutagenic and carcinogenic activity in prospective drugs, and the use of microorganisms in the manufacture of pharmaceutical products like insulin and human growth hormone.
Drug safety is a major focus of pharmaceutical microbiology. Pathogenic bacteria, fungi (yeasts and moulds) and toxins produced by microorganisms are all possible contaminants of medicines- although stringent, regulated processes are in place to ensure the risk is minimal.
Antimicrobial activity and disinfection
Another major focus of pharmaceutical microbiology is to determine how a product will react in cases of contamination. For example: You have a bottle of cough medicine. Imagine you take the lid off, pour yourself a dose and forget to replace the lid. You come back to take your next dose and discover that you will indeed leave the lid off for a few hours. What happens if a microorganism "fell in" whilst the lid was off? There are tests that look at that. The product is "challenged" with a known number of specific microorganisms, such as E. coli and C. albicans and the anti-microbial activity monitored.
Pharmaceutical microbiology is additionally involved with the validation of disinfectants, either according to U.S. AOAC or European CEN standards, to evaluate the efficacy of disinfectants in suspension, on surfaces, and through field trials. Field trials help to establish the frequency of the application of detergents and disinfectants.
Methods and specifications
Testing of pharmaceutical products is carried out according to a Pharmacopeia of which there are a few types. For example: In America, the United States Pharmacopeia is used; in Japan there is the Japanese Pharmacopeia; in the United Kingdom there is the British Pharmacopoeia and in Europe the European Pharmacopeia. These contain a test method which is to be followed when testing, along with defined specifications for the number of microorganisms allowed in each amount of product.
The specifications change depending on the product type and method in which it is introduced to the body. The pharmacopoeia also covers areas like sterility testing, endotoxin testing, the use of biological indicators, microbial limits testing and enumeration, and the testing of pharmaceutical grade water.
Journal of Pharmaceutical Microbiology follows Editorial Tracking System for quality in peer review process. Editorial Tracking is an online manuscript submission, review and tracking systems used by most of the best open access journals.
Manuscripts related to the above relevant topics can be submitted to the Journal or through online. High quality submissions are expected to maintain the standard of the journal May the wings of your work reach heights of success.
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